Junior research groups of the Corona Foundation
Established in 2008, the Corona Foundation's funding program supports young basic scientists in medicine and physicians who have distinguished themselves through excellent scientific achievements and who wish to gain professional qualifications during the funding period of five years. The funds provided, amounting to up to 1 million euros each, are used to set up their own research group in order to carry out pioneering innovative projects in translational, cardiovascular or neurovascular research, in particular preclinical or clinical studies including epidemiological and genetic studies.
- Corona junior research group
- PROMISE
- Project leader
- Dr. Steffen Tiedt
- Institution
- Institute for Stroke and Dementia Research (ISD)
- Funding
- since 2020
- Topics
- The treatment of ischemic stroke or cerebral infarction is a major challenge. In 40 percent of patients, the cause remains undetermined. In addition, the extent of neuronal damage can still not be reliably determined either in the prehospital phase or serially in the acute phase. Proteins circulating in the blood (proteome) and metabolic products (metabolome) are able to map pathophysiological processes and therefore offer a promising approach to closing the existing diagnostic gaps. A detailed recording of the proteome and metabolome is made possible by innovative omics technologies, modern high-throughput methods that create molecular profiles of cells and tissues in a short time. The project uses omics analyses to identify the characteristic molecular signatures in stroke and to use them as diagnostic tools and for personalized therapies in the future. Among other things, PROMISE will link the clinical data of 1,000 stroke patients with laboratory tests.
Source: LMU university hospital
- Corona junior research group
- Immuno-Rhythmology
- Project leader
- Dr. Sebastian Clauß
- Institution
- Department of Medicine I
- Funding
- since 2019
- Topics
- Preliminary work has shown that cardiac macrophages have a decisive influence on the electrical properties of the AV node. The funded project builds on this and aims to investigate the role of resident cardiac macrophages in the generation and transmission of electrical impulses in the heart in order to develop new innovative approaches for the diagnosis and treatment of arrhythmias. In addition to cell cultures, mouse and pig models will also be used for this purpose, in particular to enable the translation of basic scientific findings into preclinical testing in large animal models.
Source: LMU university hospital
Junior research groups of the Corona Foundation
Established in 2008, the Corona Foundation's funding program supports young basic scientists in medicine and physicians who have distinguished themselves through excellent scientific achievements and who wish to gain professional qualifications during the funding period of five years. The funds provided, amounting to up to 1 million euros each, are used to set up their own research group in order to carry out pioneering innovative projects in translational, cardiovascular or neurovascular research, in particular preclinical or clinical studies including epidemiological and genetic studies.
- Corona junior research group
- Immuno-Rhythmology
- Project leader
- Dr. Sebastian Clauß
- Institution
- Department of Medicine I
- Funding
- since 2019
- Topics
- Preliminary work has shown that cardiac macrophages have a decisive influence on the electrical properties of the AV node. The funded project builds on this and aims to investigate the role of resident cardiac macrophages in the generation and transmission of electrical impulses in the heart in order to develop new innovative approaches for the diagnosis and treatment of arrhythmias. In addition to cell cultures, mouse and pig models will also be used for this purpose, in particular to enable the translation of basic scientific findings into preclinical testing in large animal models.
Source: LMU university hospital